Staff at land-based gambling venues can help identify patrons experiencing problem gambling. They can also communicate information about responsible gambling. This review summarizes research on the strategies, practices, and policies concerning, and behaviours of, gambling venue staff’s responses towards problem gambling behaviours. A total of 49 articles were included in the review. The authors identified five key themes: (1) corporate social responsibility programs; (2) identification of patrons with problem gambling; (3) venue staff’s responses; (4) patrons’ perspectives about venue responsibilities and interactions; and (5) needs of gambling venue staff. Overall, most activity that venue staff undertake in response to problem gambling is limited to observing. There is little action beyond discussing risky behaviours with other venue staff. It is important for venue staff to be given clear guidelines on how to identify people with problem gambling and intervene appropriately.