This study aimed to identify separate gambling-related risk factors for male and female adolescents in Italy. The researchers used data from the 2014 SPS-DAP (The Department for Anti-drug Policies’ Student Population Survey). Italian students between 15 and 19 years of age were invited to participate through their school. A total of 31,661 responses were included in this study. The researchers found that gambling was more common among males than females. About 53% of males and 34% of females gambled at least once in the previous year. Males were more likely to be at risk or have problem gambling. For both males and females, gambling was linked with internet surfing, playing video games, playing sports, getting into a fight, having unprotected sex, pulling stunts, drinking alcohol at least once in the previous month, having a poor relationship with teachers, receiving pocket money from parents, and having someone in the family who gambled. Separate risk factors for males and females’ gambling behaviour were also identified.