This article is a review of past studies on educational programs and responsible gambling measures to prevent problem gambling. Only studies with low and moderate risk of bias were reviewed. The authors assessed the certainty of evidence of each measure. Two measures, educational programs and personal feedback, appeared to have an impact on decreasing gambling frequency. However, the certainty of evidence was low. The certainty of evidence of other measures was very low. The authors pointed to the need for more high-quality research. They discussed the shortcomings of current studies and areas where future research could improve.