This study sought to evaluate the GameSense prevention program’s success in reduce gambling biases and the intention to gamble among undergraduate students. Students who completed the GameSense program reported more knowledge about gambling, fewer gambling biases, and fewer intentions to gamble in the short- and long-term. These intentions did not differ whether they won, lost, or broke even when gambling. Students who did not complete the GameSense program were more willing to gamble in the future if they won during the game. These results suggest that GameSense may be an effective program to reduce gambling biases and intentions to gamble. However, more research is needed to examine the efficacy of Gamesense with real gambling games and with people who have gambling problems.