Gambling is becoming more widely available. Yet, the relationship between social media use and problem gambling is underexplored. This study examined the association between social media use and problem gambling among Czechs aged 16 and older. Males, younger people, those with lower education, and those who were unemployed or students were found to have higher scores on the Problem Gambling Severity Index (PGSI). More frequent use of social media for news, disruptive social media use behaviours (e.g., waking up at night to check social networks), and problematic social media use involving lying to others and having conflict with family over social media use were linked to higher PGSI scores.